How much is a flight from Chicago O'Hare to Santa Cruz de la Sierra?

Prices vary based on date, airline, and availability. Compare several options if you're flying between Chicago and Santa Cruz.

Pick a travel date to see today’s available fares.

Fares change often — checking several times throughout the week can make a big difference. Booking in advance often means access to lower prices for the Chicago O'Hare - Santa Cruz de la Sierra route.

Are there alternative airports near Chicago and Santa Cruz?

The two cities are about 7101 km apart. Looking beyond the main airport might reveal better options.

• Airports in Chicago: There are 3 airports in Chicago - Midway, O'Hare, Rockford.
• Airports in Santa Cruz: Santa Cruz is another nearby option to Santa Cruz - Viru Viru.

Many smaller airports are connected by direct buses or shuttles, often at low cost. If Santa Cruz has more than one airport, you can pick the most convenient for your destination.

Customize your flight from Chicago O'Hare to Santa Cruz de la Sierra

Jetcost allows you to filter by travel dates, duration, layovers, carriers, and booking providers. You’ll find direct and connecting flights, one-way or round-trip, from the best airlines and travel agencies.

Other popular destinations

Thinking about Bolivia? You might also consider: Cochabamba, La Paz, Quijarro, Santa Cruz, Tarija.

You can sort results by price, duration, or departure time to find the best option for you. When available, results always include both low-cost and traditional airlines.